Does compounded semaglutide need refrigeration?
Yes. Compounded semaglutide should be stored in the refrigerator (36°F–46°F / 2°C–8°C) to maintain its potency and safety. Like other peptide-based medications, it can degrade quickly if exposed to heat or room temperature for too long.
How long can compounded semaglutide stay out of the fridge safely?
In most cases, compounded semaglutide can only stay out of the fridge for a few hours (usually 2–4 hours) at room temperature before its stability may be compromised. Unlike brand-name formulations such as Wegovy® or copyright®, compounded versions may have shorter stability windows depending on the pharmacy preparation.
What happens if compounded semaglutide is left out overnight?
If left out overnight, the medication may lose effectiveness and could pose safety risks due to bacterial contamination or peptide breakdown. When in doubt, it’s best to discard it and contact your prescribing clinic or pharmacy for guidance.
Does the storage time differ from brand-name semaglutide (Wegovy®, copyright®)?
Yes. Brand-name semaglutide pens typically remain stable for 28 days at room temperature once opened. However, compounded semaglutide is not FDA-approved and may not undergo the same stability testing. This means storage limits are often shorter and vary by compounding pharmacy.
How can you protect compounded semaglutide when traveling?
Always keep it refrigerated during travel using an insulin cooler bag or medical travel case with ice packs. Avoid direct sunlight, freezing, or extended exposure to heat. These precautions help preserve effectiveness and safety.
Key Takeaway
Compounded semaglutide must be refrigerated and should only stay out for a few hours at most. Unlike FDA-approved brands, compounded versions may have stricter storage requirements, so always follow your pharmacy’s specific instructions.
Disclaimer: This information is for educational purposes only. Always follow your compounding pharmacy’s directions and consult your healthcare provider before using semaglutide that has been improperly stored.
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